Professor Dennis Lo
Professor Rossa Chiu
Professor Nelson Tang
Professor Chun Kwok Wong
Professor Allen K C Chan
Professor Yiu-Loon Chui
Professor Hao Sun
Professor Ping Yuan
Professor Christopher Lam
Professor Nirmal Panesar
Dr Michael H M Chan
Dr Liz Yuen
 
 
 
Chun Kwok Wong 黃振國
Professor 教授
ck-wong@cuhk.edu.hk
Biography
Professor Wong obtained his PhD degree in Immunology from the Department of Biochemistry, CUHK in 1993. This was followed by postdoctoral appointments at the Centre for Biochemical and Biophysical Science and Medicine of the Brigham and Women's Hospital, Harvard Medical School, USA (1994-1996), and the Pulmonary and Critical Care Unit at the Massachusetts General Hospital, Harvard Medical School (1996-1997). He was appointed postdoctoral research fellow in the Department from August 1997 to June 2000, Scientific Officer in July 2000, Associate Professor in February 2001, and Professor from 1 August 2009. He has also been appointed as Assistant Director of Institute of Chinese Medicine, CUHK, and Joint State Key Laboratory of Phytochemistry and Plant Resources in West China since 2009 and 2010, respectively.
 
Professor Wong is also involved in teaching medical students and Chung Chi College general education senior seminars. Currently, Professor Wong is supervising three PhD students and one MPhil student. He serves as Honorary Scientific Officer (Medical) in the diagnostic clinical chemistry laboratory at Prince of Wales Hospital.
 
Professor Wong has been the President of Hong Kong Society for Immunology and Hong Kong Society of Flow Cytometry, and current Executive Member of the Hong Kong Society for Immunology and Institute of Biology, Hong Kong Branch.
Research Interests:
His immunology research includes (1) the elucidation of cytokine and chemokine network and intracellular signal transductions of immune effector cells including eosinophils, lymphocytes, mast cells, basophils, dendritic cells, in inflammatory diseases, with recent emphasizing in pattern recognition receptors mediated innate immunity and damaging inflammation, (2) the immunopathological mechanisms of allergic diseases, autoimmune diseases, infectious diseases and diabetes mellitus, with interdepartmental collaboration and (3) the immunomodulatory, anti-tumor and anti-allergic activities of traditional Chinese medicine. Immunoassay, flow cytometry, molecular technology and protein array method have been applied in above studies. He has published over 165 refereed papers in international journals and book chapters.
Illustrations of the 2 major research areas:
(1) Cytokine and chemokine network
(2) Intracellular signal transductions
 
 
 
 
Ten Representative Publications in 2007-2012:
Wong CK, Cheung PFY and Lam CWK. Leptin-mediated cytokine release and migration of eosinophils: implications for immunopathophysiology of allergic inflammation. Eur J Immunol 2007; 37: 2337-2348
Wong CK, Wong BCK, Chan KCA, Joynt GM, Yap YHY, Lam CWK, Lee N, Lee SS, Cockram CS, Sung JJY, Chan PKS, Lo YMD and Tang JW. Cytokine profile in fatal human immunodeficiency virus-tuberculosis-Epstein-Barr virus-associated hemophagocytic syndrome. Arch Int Med 2007; 167:1901-1903.
Lee N*, Wong CK*, (*Equal first author), Chan PKS, Lun SWM, Lui G, Wong B, Hui DSC, Lam CWK, Cockram CS, Choi KW, Yeung ACM , Tang Julian W , Sung JJY . Hypercytokinemia and Hyperactivation of p38 Mitogen-Activated Protein Kinase in Severe Human Influenza A Infections. Clin Infect Dis 2007; 45: 723-731.
Cheung PFY, Wong CK* (*Equal first author), and Lam CWK. Molecular mechanisms of cytokine and chemokine release from eosinophils activated by IL-17F and IL-23: implications for Th17 lymphocyte-mediated allergic inflammation. J Immunol 2008; 180:5625-35.
Wong CK, Lit LCW, Tam LS, Li EK, Wong PTY, Lam CWK. Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity. Clin Immunol 2008; 127:385-393.
Wong CK, Hu SQ, Cheung PFY and Lam CWK. Thymic Stromal Lymphopoietin Induces Chemotactic and Pro-survival Effects in Eosinophils: Implications in Allergic Inflammation. Am J Respir Cell Mol Biol 2010; 43: 305-15.
Wong CK, Cao J, Yin YB and Lam CWK. IL-17A activation on bronchial epithelial cells and basophils: a novel inflammatory mechanism. Eur Respir J 2010; 35: 883-93.
Wong CK, Chen DP, Tan LS, Li EK, Yin YB, and Lam CW. Effects of inflammatory cytokine IL-27 on the activation of fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Res Ther 2010; 12: R129.
Cao J, Wong CK*(*Equal first author), Yin YB and Lam CWK. Activation of Human Bronchial Epithelial Cells by Inflammatory Cytokines IL-27 and TNF-α: Implications for Immunopathophysiology of Airway Inflammation. J Cell Physiol 2010; 223: 788-97.
Wong CK, Leung KML, Qiu HN, Chow JYS, Choi AOK and Lam CWK. Activation of Eosinophils Interacting with Dermal Fibroblasts by Pruritogenic Cytokine IL-31 and Alarmin IL-33: Implications in Atopic Dermatitis. PLoS One 2012; 7: e29815.